Role of peritoneal transport characteristics and nutritional status in evaluation of peritoneal dialysis adequacy
10.3760/cma.j.issn.1674-635X.2009.01.008
- VernacularTitle:腹膜转运和营养状况在腹膜透析充分性评价中的作用
- Author:
Rui ZHANG
;
Yeping REN
;
Bing LI
;
Tianrong JI
;
Shuying LI
- Publication Type:Journal Article
- Keywords:
Peritoneal dialysis;
Peritoneal transport;
Dialysis adequacy;
Nutrition
- From:
Chinese Journal of Clinical Nutrition
2009;17(1):24-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the influence of peritoneal transport characteristics on nutritional status of peritoneal dialysis patients and estimate the role of peritoneal transport characteristics and nutritional status in evaluation of peritoneal dialysis adequacy. Methods Peritoneal transport properties (D/Pcr) were evaluated by Short Peritoneal Equilibration Test and then 53 cases were divided into high transport group (D/Pcr ≥0. 65) and low transport group (D/Pcr < 0. 65). Urea kinetics (Kt/v) and total clearance of creatinine (TCcr) were calcu- lated. Serum albumin (ALB), prealbumin, transferring (TF), hemoglobin (Hb), lean body mass (LBM) and LBM% were examined or calculated. Subjective global assessment (SGA) was used to evaluate the nutritional sta- tus of patients. Results There were 30 cases in high transport group and 23 cases in low transport group. D/Pcr (0. 82±0.15 vs. 0. 55±0. 08, P < 0. 01), TCcr (62. 93%±25. 98% vs. 49. 69%±16. 92% , P < 0. 05) and age were significantly higher in high transport group than those in low transport group, while ALB, TF, Hb, LBM% , and SGA were significantly lower than those in low transport group (P < 0.05). ALB was negatively cor-related with Kt/v (r= -0.2708, P<0. 05). Conclusions High peritoneal transport patients have better solute clearance but worse nourishment status compared with low transport ones. Nutritional status is one of the factors to evaluate dialysis adequacy. Nutrition management and guidance should be strengthened for the continuous ambula- tory peritoneal dialysis patients, especially for the elderly ones.
