The correlation study of 1-hour postload plasma glucose level and carotid intima-media thickness in elderly male patients with hypertension
10.3760/cma.j.issn.0254-9026.2009.05.003
- VernacularTitle:负荷后1小时血糖与老年男性高血压患者颈动脉内中膜厚度的相关性
- Author:
Pengying GU
;
Shandong YE
;
Shiyang ZHANG
;
Meiguang LI
;
Weidong WANG
;
Dongmei KANG
- Publication Type:Journal Article
- Keywords:
Blood glucose;
Carotid arteries;
Tunica intima;
Atherosclerosis;
Hypertension
- From:
Chinese Journal of Geriatrics
2009;28(5):371-373
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the correlation between 1-hour postload plasma glucose and carotid intima-media thickness (IMT) in elderly male patients with hypertension.Methods One hundred and twenty six elderly male patients with hypertension were enrolled and divided into four groups: normal glucose tolerance with normal 1 h plasma glucose (1 hPG) group (low-NGT, n=42); normal glucose tolerance with high lh plasma glucose group (high-NGT, n=23);impaired glucose tolerance group (IGT, n=27) and diabetic group (n=84). The differences of blood pressure, blood glucose, blood lipid and intimia-media thickness among groups were analyzed.Results OGTT 1 hPG in high-NGT group was similar with IGT group[(12.0±1.1)mmol/L vs. (11.1±1.8)mrnol/L, P>0. 053 ,but significantly higher than that in Iow-NGT group ((12.0±1.1)mmol/L vs. (9. 1±1.4) mmol/L, P<0.01]. The value of IMT was gradually increased in four groups (P<0.05) and it was (1.02±0. 12) mm in high-NGT group. OGTT 1 hPG was the independent risk factor for IMT(P< 0.01).Conclusions OC-TT 1h plasma glucose is associated with atherosclerosis in elderly male hypertensive people.