Effect of differential electroacupuncture frequencies on behavior of acute stress depression model of C57BL/6 mice

VernacularTitle:不同频率电针对急性应激模型C57BL/6小鼠抑郁行为的影响
Author: Weidong LI ; Jun LU ; Ya TU
Publication Type:Journal Article
Keywords: Depression; Electroacupuncture; Forced swimming tests; Tail suspension test
From: Chinese Journal of Behavioral Medicine and Brain Science 2009;18(2):134-135
CountryChina
Language:Chinese
Abstract: Objective To explore the effect of different frequencies interference of electoracupuncture on acute stress of C57BL/6 mice. Methods Thirty male C57BL/6 mice were randomly divided into model group,2Hz electroacupunture group and 100 Hz electroacupunture group.After interfering 7 days by electroacupuncture,all the mice were carried forced swimming tests and tail suspension test,and the immobility time in 5 minutes were taken down. Results The immobility time of forced swimming test and tail suspension test of 2 Hz eletroacupuncture group(32.00±14.73)s,(72.50±20.44)s was shorter than those of 100 Hz electoracupuncture group(145.60±34.62)s,(124.22±21.67)s( P <0.05); and the immobility time of 2 Hz eletroacupuncture group was shorter than that of model group(129.50±33.94)s,(142.23±20.05)s( P <0.05); but the immobility time of 100 Hz electroacupuncture group was no difference with that of model group( P >0.05). Conclusions The effect of 2 Hz eletroacupuncture could improve the behaviors of the acute stress of C57BL/6 mice and had the more effectiveness on anti-depression.