Metastasis and micrometastasis in ultra-low rectal cancer

VernacularTitle:Miles术直肠标本淋巴结分布及转移研究
Author: Xuefeng GUO ; Meijin HUANG ; Ping LAN ; Hui PENG ; Jianping WANG
Publication Type:Journal Article
Keywords: Rectal neoplasms; Lymph nodes; Neoplasms metastasis
From: Chinese Journal of General Surgery 2009;24(5):402-405
CountryChina
Language:Chinese
Abstract: Objective To study cancer metastasis in mesorectum and ischiorectal loss in cases of ultra-low rectal cancer and evaluate the rationale of Miles procedure. Methods Whole-mount slice and tissue mieroarray technique were used to study the dissected specimen from 23 cases of uhra-low rectal cancer for metastatic lymph nodes. Result 415 lymph nodes were harvested in 23 mesorectum specimen, 169 and 59 lymph nodes were metastasic and micrometastasie respectively. 12 eases were diagnosed with metastasis, 4 cases were found to have micrometastasis. Metastatic lymph nodes in the lateral and anterior mesorectum were 29.0% (49/169) and 17.2% (29/169) respectively. There were 2 patients with metastasis and 1 with micrometsstssis in ischiorectal fossa lymph nodes, accounting for 13% patients. Conclusion Regional metastasis exists in ultra-low rectal cancer and its incidence varies in different location of mesorectum and ischiorectal fessa. The value of Miles procedure as the standard therapy for ultra-low rectal cancer should undergo an evaluation.