Twenty-nine cases of primary Sjogren's syndrome complicated with malignancies

VernacularTitle:原发性干燥综合征合并恶性肿瘤29例分析
Author: Sheng FENG ; Shumin YAN ; Li SU ; Lijuan GOU ; Xiaofeng ZENG ; Fengchun ZHANG ; Yi DOING ; Yan ZHAO
Publication Type:Journal Article
Keywords: Sjogren's syndrome; Lymphoma,non-Hodgkin's; Neoplasms
From: Chinese Journal of Rheumatology 2009;13(5):336-338
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical features and risk factors of primary Sjogren's syndrome (pSS) patients with malignancies.Methods The clinical features of 29 pSS patients with malignancies from January 1985 to March 2008 were retrospectively analyzed.Results The ratio of pSS with malignancies to all hospitalized pSS patients from January 1985 to March 2008 was 2.2%.In these patients,8 were lymphoma,4 were breast cancers,2 were myeloma,2 were thymoma,2 were lung cancer,2 were gastric carcinoma,2 were hepatoma,2 were colon carcinoma and 2 were tongue cancer.Uterine cervix cancer,renal carcinoma,thyroid carcinoma and carcinoma of parotid gland each were fund in this series of patients.Conclusion The most common malignancy in pSS is lymphoma and the major of pathological type is B cell non-Hodgkin's lymphoma.