Liver diseases in adult-onset Still's disease

VernacularTitle:成人Still病108例肝脏损害分析
Author: Jianzhong LIU ; Yanfang LIU ; Guanglan ZHANG ; Xiaolei WANG ; Jupeng TAN ; Ming HAN
Publication Type:Journal Article
Keywords: Still's diseases,adult.onset; Liver diseases
From: Chinese Journal of General Practitioners 2009;8(5):337-339
CountryChina
Language:Chinese
Abstract: Clinical data of 108 patients with adult-onset Still's disease(AOSD)were analyzed.The results showed that 56 patients(51.9%)developed liver damage and abnormal liver functioil(alanine aminortransferase and aspartate aminortransferase were significantly increased).Gender,age,time from disease onset to confirmed diagnosis,fever,rash,arthritis,pharyngeal pain,splenomegaly,lymphadenopathy,anemia,leukocvtosis,thrmbocytosis,and increased erythrocyte sedimentation rate,serum C-reactive protein,and serum iton protein showed no significant difierence between the two groups (P＞0.05).Clinical symptoms of liver damage were atypical.Among the 56 patients with liver damage,8 were presented with gastrointestinal symptoms,and 24 showed enlarged liver iu B.ultrasound examination.Our results suggest the prevalence of liver damage in AOSD patients may be hiSh,which could attribute to the disease itself and the medication.The patients would expect good response to corticosteroid treatment and satisfactory outcomes.