Thirty Cases Clinical Study on the Treatment of Premature Ovarian Failure with the BuShen NingXin YiJing Pill
10.3760/cma.j.issn.1673-4246.2009.03.019
- VernacularTitle:补肾宁心益经丸治疗卵巢早衰30例临床观察
- Author:
Xujing LI
;
Shifeng HAO
- Publication Type:Journal Article
- Keywords:
Premature ovarian failure: Herbal medicine: BuShen NingXin YiJing Pill
- From:
International Journal of Traditional Chinese Medicine
2009;31(3):229-230
- CountryChina
- Language:Chinese
-
Abstract:
Objective The purposes of the present study are to investigate the effects and mechanisms of Bu Shen Ning Xin Yi Jing Pill on premature ovarian failure (POF) through a clinical study. Methods Sixty women with POF were administered and randomized into the treatment group and the control group. Every group had thirty cases. Patients in the treatment and control groups were requested to have the Bu Shen Ning Xin Yi Jing Pill and the Liu Wei Di Huang Pill, respectively. Six-month duration was considered as a therapeutic course. The serum levels of follicle stimulating hormone (FSH) and estradiol (E2) were determined by the chemistry luminescence method. Differences between the treatment and control groups were investigated.Results Improved menstruation were revealed in both groups and the treatment group showed significant improvement than the control group (P<0.01). In the treatment group, serum FSH levels sharply dropped after treatment, while the serum E2 levels significantly elevated compared with those of prior-treatment (P<0.01) . The total effective rate in the treatment group was 70% (21 cases), whereas 40% in the control group (12 cases). The difference had statistical significance (P<0.01) .Conclusion The BuShen NingXin YiJing Pill is effective in the treatment of premature ovarian failure via significant improvements in the clinical symptoms and balance of the endocrine hormones.