p53 and PCNA in non-small cell lung cancer
10.3760/cma.j.issn.1673-422X.2009.04.015
- VernacularTitle:p53和PCNA与非小细胞肺癌
- Author:
Baorong XIAO
;
Zhaofeng ZHU
;
Xin LU
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Genes,p53;
Proliferating cell nuclear antigen;
Radia-tion tolerance;
Prognosis
- From:
Journal of International Oncology
2009;36(4):283-285
- CountryChina
- Language:Chinese
-
Abstract:
p53 Gene and proliferating cell nuclear antigen (PCNA) are both related closely to the ra-diotherapy of non-small cell lung cancer(NSCLC). The life span of NSCLC patients with both p53 and PCNA positive is shorter than that of NSCLC patients with both p53 and PCNA negative. Studying the expression of p53 and PCNA in NSCLC, and their relationship with the radiosensitivity and prognosis of NSCLC can play a positive role in individualized treatment and increasing curative effect.
