Animal models of colorectal cancer and liver metastases
10.3760/cma.j.issn.1673-4203.2009.05.011
- VernacularTitle:大肠癌肝转移动物模型的研究进展
- Author:
Rongjiao YANG
;
Xingxiang HE
- Publication Type:Journal Article
- Keywords:
colorectal cancer;
liver metastases;
mouse models
- From:
International Journal of Surgery
2009;36(5):316-319
- CountryChina
- Language:Chinese
-
Abstract:
The liver is the most common site of distant metastasis of colorectal cancer. In order to study colorectal cancer metastasis to the liver, establishing and choosing appropriate mouse model is crucially im-portant. In this review, we mainly discuss the mouse models of colorectal cancer and liver metastases: Tumor fragments or cancer cells orthotopic transplant to eoloncecal part, injecting cancer cells into the spleen, portal injection of cancer cells, colorectal cancer implantation to the subcapsular of the liver.
