Signal transduction pathways of BMSC differentiating to osteoblast cuo
10.3760/cma.j.issn.1673-4203.2009.05.015
- VernacularTitle:BMSC向成骨细胞分化的信号传导通路
- Author:
Changjun GUO
;
Qinming FEI
;
Jian ZHANG
- Publication Type:Journal Article
- Keywords:
BMSC;
osteoblast;
signal transduction pathwayDOI:10.3760/cma.j.issn.1673-4203.2009.05.015
- From:
International Journal of Surgery
2009;36(5):328-332
- CountryChina
- Language:Chinese
-
Abstract:
Bone mesenchymal stem cell is a kind of multi-potential stem cells and can differentiate into osteoblast. The differentiation has membrane bone formation and enchondral bone formation two channels, and is regulated by numerous signal transduction pathways. According to related literatures, we review the signal transduction pathways of BMP/Smads, Runx2/osterix, Hedgehog, Wnt/β-Catenin and MAPK.
