Effect of rocuronium on entropy to endotracheal intubation during propofol anesthesia induction
10.3760/cma.j.issn.1673-4904.2009.15.006
- VernacularTitle:罗库溴铵对丙泊酚麻醉诱导气管插管时熵指数的影响
- Author:
Xiuying WANG
;
Kechang HUANG
;
Changxue HUANG
;
Cui HE
;
Jianhua LI
- Publication Type:Journal Article
- Keywords:
Intubation,endotracheal;
Propofol;
Entropy;
Rocuronium
- From:
Chinese Journal of Postgraduates of Medicine
2009;32(15):14-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of rocuronium on entropy to endotracheal intubation during anesthesia induction with propofol. Methods Forty patients anesthetized induction with propofol using a target-controlled infusion were randomly divided into two groups: rocuronium group (R group, 20 cases) received 0.6 mg/kg rocuronium or saline group (S group, 20 cases) received saline. 2-3 min later, endotracheal intubation was performed. Response entropy(RE) and state entropy(SE) were recorded during baseline(Ta), at steady state(Tb), 2 min after rocuro nium or saline administration (Tc) and 0, 1, 2 and 3 min after endotracheal intubation (T0, T1, T2, T3). Results At T2, the RE-SE was higher in S group than that in R group. Endotracheal intubation induced increasing in RE and SE. Comparing T2 and T0 values in R group and S group, SE increased from 42 ± 7 to 50 ± 8 and 43 ± 13 to 55 ± 12, and RE increased from 45 ± 6 to 54 ± 9 and 48 ± 16 to 66 ± 15, respectively. At T0, RE and RE-SE were higher in S group. Conclusion Rocuronium affects RE-SE and RE and RE-SE responses to endotracheal intubation and may confound interpretation of entropy monitoring.
