Analysis of the relationship between bladder cancer mortality and ultraviolet irradiation

VernacularTitle:中国膀胱癌死亡率与紫外线照射的关系
Author: Wanqing CHEN
Publication Type:Journal Article
Keywords: Bladder neoplasms; Mortality; Ultraviolex
From: Chinese Journal of Urology 2009;30(6):405-407
CountryChina
Language:Chinese
Abstract: Objective To investigate the relationship between bladder cancer and ultraviolet ir-radiation for providing ecological information on cancer prevention and control. Methods The cancer death data were retrieved from second cancer death survey, 1990-1992, China. The estimated daily cloud-adjusted ambient solar UVB irradiance at 305 nanometers (mW/m2), was obtained from NASA database the total ozone mapping spectrometer (TOMS) using ArcGIS 9.1 software to measure the county level average daily irradiance over the whole year. Negitive binomial regression modeling by SAS statistics software was adopted for analysis. Results Mortality of bladder cancer was negitively related with UVB irradiation in both sexes and in different sexes and locations. Adjusted mortality fell by 0. 56% per unit of UVB (rate ratio 0. 9944, 95%CI 0.9911-0.9977, P=0.0013). This down-trend was stronger for female (0.66% per unit of UVB) than for male (0.51%) and stronger in rural areas (0.58%) than in urban areas (0.55%). Conclusions Sunshine irradiation might reduce the mortality of bladder cancer probably by increasing the concentration of vitamin D in the body. Further study would be necessary to explain the reaction mechanisam.