The changes of myocardial enzymes and troponin I in patients with hepatocellular carcinoma closed to heart after high intensity focused ultrasound ablation

VernacularTitle:高强度聚焦超声治疗靠近心脏肝癌后心肌酶谱和肌钙蛋白Ⅰ的变化
Author: Wenting GONG ; Xiaoxia LI ; Chengbing JIN ; Hui ZHU ; Lifeng RAN ; Zhibiao WANG
Publication Type:Journal Article
Keywords: Ultrasound,high-intensity focused; Carcinoma,hepatocellular; Enzymes; Troponin I
From: Chinese Journal of Ultrasonography 2009;18(5):422-424
CountryChina
Language:Chinese
Abstract: Objective To investigate the influences of heart in patients with hepatocellular carcinoma closed to heart after high intensity focused ultrasound ablation(HIFU). Methods Thirty four patients with hepatocellular carcinoma closed to heart received detecting the values of periphery blood aspartate transarninase(AST), creatine kinase (CK), CK-MB, α-hydroxybutyrate dehydrogenase (α-HBDH), lactate dehydrogenase(LDH), myoglobin(Myo) and troponin I (cTnI) before and 1,3, 7 days after HIFU respectively. ECG was monitored in all patients simultaneously. Results The values of AST,CK,CK-MB,α-HBDH, LDH and Myo increased 1 day after HIFU significantly (P<0.05), which decreased greatly 3 days after HIFU and nearly recovered well (P>0.05) 7 days after HIFU. However, the value of cTnI and ECG were normal before and after HIFU. Conclusions No obvious myocardium injury was found after HIFU in patients with hepatocellular carcinoma dosed to heart, cTnI may be an important marker to evaluate myocardium injury after HIFU.