The correlation of serum creatine kinaseisoenzyme-MB and the prognosis of patients with acute coronary syndrome
10.3760/cma.j.issn.1673-4904.2009.16.010
- VernacularTitle:血清肌酸激酶同工酶-MB水平与急性冠脉综合征患者预后的相关性探讨
- Author:
Ling CHEN
;
Jian ZENG
;
Xueying LIN
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Creatine kinase,MB form;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2009;32(16):22-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of serum ereatine kinase iseenzyme-MB (CK-MB) and recent cardiac events(30 days, 180 days) and late cardiac events (360 days) in patients with acute coronary syndrome (ACS). Methods Serum creatine kinase (CK) and CK-MB in 168 patients with ACS were measured, and these patients were divided into four groups according to the levels of CK and CK-MB. The occurrence of cardiac events analysis of CK and CK-MB was followed up for 30, 180 and 360 days and the relationship between the occurrence of cardiac events and the levels of CK and CK-MB were studied. Results There was statistical correlation between increased CK-MB and abnormal ECG Q wave, ST segment change (P< 0.05), 168 patients had followed up 30, 180 and 360 days, in which cardiac events happened in 57 common patients (64 examples), 27 examples (16.1%) happened in the recent cardiac event, and 37 examples(22.0%) happened in the late cardiac event. The cardiac event and CK-MB elevation had statistical correlation (P<0.05). Conclusion ACS patients with increased CK-MB levels prompt a poor prognosis, and could be an independent indicator of recent and late cardiac events in patients with ACS.
