Comparison of different metastatic lymph node classification on prognosis prediction in patients with node-positive colon cancer

VernacularTitle:不同淋巴结转移N分级方法对结肠癌的预后比较
Author: Maorong SHEN
Publication Type:Journal Article
Keywords: Colonic neoplasms; Lymphatic,metastasis; Lymph nodes; Prognosis
From: Chinese Journal of Postgraduates of Medicine 2009;32(17):29-30
CountryChina
Language:Chinese
Abstract: Objective To compare number and level of positive lymph nodes (PLNs) to see which is a better predictor of prognosis for node-pesitive colon cancer. Methods Seventy-eight patients had undergone curative resection for node-positive colon cancer. Calculated the cumulative 3-year, 5-year survival rates and explored the relation to survival rates between number (pN1/pN2) and level (level Ⅰ/Ⅱ)of PLNs. Results The 3-year, 5-yesr survival rotes of colon cancer with PLNs was 73.1%(57/78), 65.4%(51/78). There was statistical difference of 3-year, 5-year survival rates between pN1 group and pN2 group [77.8% (42/54)vs 62.5% (15/24), 72.2% (39/54)vs 50.0% (12/24),P =0.004], but no statistical difference between level Ⅰ group and level Ⅱ group [77.5 %(31/40) vs 68.4%(26/38), 67.5%(27/40) vs 63.2% (24/38),P=0.349]. Conclusion In node-positive colon cancer, number of PLNs predicts prognosis better than level of PLNs.