Mesenchymal stromal cells for cerebral infarction
10.3760/cma.j.issn.1673-4165.2009.05.009
- VernacularTitle:骨髓基质细胞治疗脑梗死的研究现状
- Author:
Yanhui XING
;
Zhiyi HE
;
Liping LIU
- Publication Type:Journal Article
- Keywords:
bone marrow cells;
stromal cells;
cerebral infarction;
meseucbymal stemcell transplantation
- From:
International Journal of Cerebrovascular Diseases
2009;17(5):373-377
- CountryChina
- Language:Chinese
-
Abstract:
Although there are many drugs for the treatment'of cerebral infarction, no satisfactory efficacy has achieved. Mesenehymal stromal cells (MSCs) have multilineage differentiation potential and self-renewing capability, and can differentiate into neurons. The transplanted MSCs can improve neurological deficit after cerebral infarction, promote the recovery of neurological function, and thereby reduce the disability of cerebral infarction through the mechanisms such as releasing nutritional factors and growth nutritional factors, promoting angiogenesis. The use of MSCs for cell transplantation is likely to be an ideal means in the treatment of cerebral infarction.