Application of glomerular filtration rote estimation equations in chronic glomerulonephritis
10.3760/cma.j.issn.1008-6315.2009.06.017
- VernacularTitle:肾小球滤过率评估方程在慢性肾小球肾炎患者中的应用评价
- Author:
Xun LIU
;
Cheng WANG
;
Hua TANG
;
Zhujiang CHEN
;
Zengchun YE
;
Tanqi LOU
- Publication Type:Journal Article
- Keywords:
Chronic glomerulonephritis;
Estimation equation;
Glomerular filtration rate
- From:Clinical Medicine of China
2009;25(6):607-609
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the applicability of glomerular filtration rate (GFR) caJcuated by Cock-croft-Gault equation, MDRD1 equation and abbreviated MDRD equation in the chronic glomerulonephritis. Methods 143 chronic kidney disease(CKD) patients diagnosed in our hospital from January 2005 to December 2007 were investigated. Glomerular filtration rate(GFR) was estimated with Cockcroft-Gault equation, MDRD1 equation and ab-breviated MDRD equation. The accuracy of estimated GFRs was compared with 99Tcm-DTPA-GFR in chronic glomer-ulonephritis patients. Results Bland-Altman analysis demonstrated that Cockcroft-Gault equation was more consist-ent with GFR and sGFR than the other equations. Linear regression analysis showed that the slopes of Cockcroft-Gault equation were closer to the identical line,with a smaller bias and higher accuracy . When compared, the bias as well as accuracy of estimated GFRs with sGFR in different stages of CKD,Cockcroft-Gault equation showed good results. Condusion When plasma creatinine is checked with enzymatic method, Cockcroft-Gault equation is more appropriate than MDRD1 equation and abbreviated MDRD equation for estimating renal function in chronic glomeru-lonephritis patients.
