Correlation analysis between cerebral microbleed and stroke subtype
10.3760/cma.j.issn.1008-6315.2009.06.024
- VernacularTitle:脑微出血与脑卒中亚型的相关分析
- Author:
Jingbiao ZHANG
;
Jing WANG
;
Yong ZHANG
;
Zhenzhi LI
- Publication Type:Journal Article
- Keywords:
Stroke;
Cerebral infarction;
Hemosiderin;
Intracerebral hemorrhage;
Magnetic reso-nance imaging
- From:
Clinical Medicine of China
2009;25(6):632-634
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of microbleeds on the onset and development of different types of stroke. Methods According to stroke subtypes, 163 patients were classified into lacunar infarction (n= 56), transient iscbemia attach (n=31), atherothrombotic infarction (n=37), intracerebral hemorrhage (n=39), and control groups (n=43). Suaceptibility-weighted imaging , T1WI, T2WI and diffusion-weighted imaging were performed with 3.0 T system to observe cerebral microbleed and infarction. Results The incidence and the number of micrehleeds were significantly greater in patients with intracerebral hemorrhage (75.6% and 14.5±11.6, re-spectively),then lacunar infarction and therothrombetic infarction atherothrombotic infarction [(55.3% and 8.1± 3.4), (37.8% and 4.5±2.6)] and the incidence and the number of microhleeds in above groups are higher than transient ischemia attach (9.7% and 0.3±0.1), and controls (9.3% and 0.2±0.1) (P<0.01). There was a correlation between the number of microbleeds and the severity of lacunar infarction, aslo a correlation between the number of microbleeds and the number of intracerebral hemorrahages (r=0.402, P<0.001). Conclusion Microb-leeds are closely associated with stroke, which may indicate more advanced microangiopathy and higher risk of bleeding.
