The role of synaptic plasticity in vascular cognitive impairment
10.3760/cma.j.issn.1673-4165.2009.05.012
- VernacularTitle:突触可塑性在血管性认知障碍中的作用
- Author:
Zili HUANG
;
Xiuyan HUANG
;
Benxiao WANG
;
Ping XU
- Publication Type:Journal Article
- Keywords:
cerebrovascular disorders;
cognition disorders;
neuronal plasticity;
synaptophysin
- From:
International Journal of Cerebrovascular Diseases
2009;17(5):386-389
- CountryChina
- Language:Chinese
-
Abstract:
Synaptic injury exists in the early period of vascular cognitive impairment (VCI), and it is closely correlated with the cognitive dysfunction, however, its specific mechanism remains unclear. To study the plasticity of synaptic morphological structure, the plasticity of the efficiency of synaptic transmission as well as the role and mechanism of synapic proteins in the onset of VCI will help to further clarify the pathogenesis of VCI, and thus more effectively combat VCI.