Iron overloading and brain injury following intracerbral hemorrhage
10.3760/cma.j.issn.1673-4165.2009.05.013
- VernacularTitle:铁超载与脑出血后脑损伤
- Author:
Dongxun XU
;
Yousong YANG
- Publication Type:Journal Article
- Keywords:
intracerebral hemorrhage;
iron ion;
brain injury;
iron chelator
- From:
International Journal of Cerebrovascular Diseases
2009;17(5):390-392
- CountryChina
- Language:Chinese
-
Abstract:
Intracerebral hemorrhage (ICH) is a common nervous system disease, its mortality and disability are very high. However, the mechanisms of brain injury after ICH have not yet been fully explained. "[he latest studies have suggested that iron overloading plays an important role in the brain injury after ICH. This article reviews the advances in research on the distribution and function of iron in the brain, the mechanisms of brain injury caused by iron overloading after ICH as well as the use of iron chelator.