The cost-effect iveness analysis of patients with urinary tract infection treated with moxifloxacin and gatifloxacin

VernacularTitle:莫西沙星与加替沙星治疗泌尿系统感染的成本-效果分析
Author: Yinghao ZHANG ; Jianzhen LU
Publication Type:Journal Article
Keywords: Moxifloxacin; Gatifloxacin; Urinary tract infection; Cost-effectiveness analysis
From: Chinese Journal of Postgraduates of Medicine 2009;32(18):17-19
CountryChina
Language:Chinese
Abstract: Objective To estimate the curative effect and cost-effectiveness of moxifloxacin and gatifloxacin for treatment of urinary traet infection. Methods Eighty patients with urinary tract infection were randomly divided into treatment group (40 cases) and control group (40 cases). The patients in treatment group were given 400 mg moxifloxacin once a day for 7 d, while in control group were given 400 mg gatifloxacin once a day for 7d. Results The total clinical effective rate of treatment group and control group were 95.0%(38/40) and 92.5%(37/40) respectively, and the bacterial eliminating rate were 77.50% (31/40) and 76.92% (30/39), and the rate of adverse reaction were 5.0% ( 2/40 ) and 7.5% (3/40) respectively. There was no significant difference between two groups (P>0.05). The cost-effectiveness ratio of moxifloxacin was 2296 and 779 for gatifloxacin (P<0.01). Conclusion The therapeutic scheme of gatifloxacin seems to be the best one for treating urinary tract infection.