Plasma norepinephrine levels in infants and children with congestive heart failure.
- Author:
Sang Woog LEE
;
Myung Sung KIM
;
Sang Lak LEE
;
Tae Chan KWON
;
Chin Moo KANG
- Publication Type:Original Article
- Keywords:
Norepinephrine;
Congestive heart failure
- MeSH:
Arterial Pressure;
Cardiac Catheterization;
Cardiac Catheters;
Child*;
Estrogens, Conjugated (USP)*;
Heart;
Heart Diseases;
Heart Failure*;
Humans;
Infant*;
Norepinephrine*;
Plasma*;
Sympathetic Nervous System;
Ventricular Pressure
- From:Journal of the Korean Pediatric Society
1993;36(7):982-986
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To characterize the sympathetic nervous system response to congestive heart failure in infants and children, plasma norepinephrine levels were measured in 29 patients aged 4 months to 15 years undergoing routine cardiac catheterization at Dong San Hospital, Keimyung University during the period of 4 months from November 1990 to February 1991. Plasma norepinephrine levels were significantly higher in patients with heart disease and congestive heart failure than in those without congestive heart failure(P<0.001). A significant association was found between the level of plasma norepinephrine and severity of the symptoms of congestive heart failure. Plasma norepinephrine levels correlated well with size of the shunt (Qp/Qs)(gamma=0.75), degree of pulmonary arterial pressure (gamma=0.79) and degree of right ventricular pressure (gamma=0.82).
