Regional differences in the response of human preadipocytes to renin-angiotensin system blockers in adiponectin expession
10.3760/cma.j.issn.1000-6699.2009.03.028
- VernacularTitle:RAS阻断剂对人前脂肪细胞脂联素表达的部位特异性影响
- Author:
Rong LUO
;
Fengshi TIAN
;
Yan WU
;
Dongjie BAN
- Publication Type:Journal Article
- Keywords:
Renin-angiotensin system;
Humans;
Preadipocytes;
Adiponectin;
Body regions
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(3):328-330
- CountryChina
- Language:Chinese
-
Abstract:
The adiponeetin mRNA expression and secretion of human omental and subcutaneous preadipocytes were increaed by renin-angiotensin system (RAS) bloekers. Compared with thiazolidinedione, RAS blockers have stronger effects on human omental preadipoeytes in adiponeetin mRNA expression and secretion,suggesting a potential benefit of RAS blockers on metabolic syndrome with characteristic intra-abdominal obesity.
