Effect of thyrocytes from transgenic mice expressing thyroid specific MHC class Ⅱ on autologous T lymphocyte in vitro
10.3760/cma.j.issn.1000-6699.2009.03.010
- VernacularTitle:表达MHC Ⅱ类分子的转基因鼠甲状腺细胞对自身T细胞的影响
- Author:
Yushu LI
;
Xiaohui YU
;
Xiaochun TENG
;
Haixia GUAN
;
Chenling FAN
;
Zhongyan SHAN
;
Weiping TENG
- Publication Type:Journal Article
- Keywords:
Thyrocytes;
Major histocompatibility class Ⅱ;
T-lymphocytes
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(3):278-279
- CountryChina
- Language:Chinese
-
Abstract:
Thyrocytes expressing MHC class Ⅱ molecules were separated from transgenic mice and were co-cultured with autologous spleen T lymphocytes. T cells did not proliferate and were not activated, but CD4+ T cells were promoted into apoptosis.
