Response of glucagon to the changes of glucose and blood pressure in elderly patients with type 2 diabetes
10.3760/cma.j.issn.1000-6699.2009.03.015
- VernacularTitle:老年2型糖尿病患者胰高血糖素对血糖、血压变化的反应
- Author:
Hui ZHU
;
Yingli LU
;
Huixin ZHANG
;
Fangzhen XIA
;
Ting GU
;
Yi CHEN
;
Tingting YE
;
Hua YANG
- Publication Type:Journal Article
- Keywords:
Glucagon;
Diabetes mellitus,type 2;
Hypertension
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(3):295-296
- CountryChina
- Language:Chinese
-
Abstract:
The response of glueagon to the change of glucose and its relation to blood pressure in 71 eidely patients with type 2 diabetes was investigated. The results showed that the postprandial increment of glucagon in the group of patients with postprandial 2h plasma glucose increment<2.5 mmol/L was significantly higher than that in the group with plasma glucose inerement≥ 2.5 mmoi/L (P<0. 05). The postprandial increment of glucagon in patients with normal blood pressure was significantly higher than that in patients with hypertension (P<0.05). The results suggest that the decreased response of glucagon to the change in plasma glucose in elderly patients with type 2 diabetes is related to increased blood glucose and high blood pressure.