Plasma visfatin levels in subjects with different states of glyeemia and its related factors
10.3760/cma.j.issn.1000-6699.2009.03.016
- VernacularTitle:不同血糖状态人群血浆内脂素水平及其相关因素
- Author:
Mei LI
;
Jirui HE
;
Anmin NI
- Publication Type:Journal Article
- Keywords:
Visfatin;
Diabetes mellitus,type 2;
Obesity
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(3):297-298
- CountryChina
- Language:Chinese
-
Abstract:
Fasting plasma visfatin was determined in subjects with various types of glucose tolerance. Visfatin level was (17.64±1.37)μg/L in subjects with normal glucose tolerance,and rose to (27.42±1.34) μg/L(P<0.05) in those with impaired glucose tolerance or impaired fasting glucose, and to(26.55 ± 1.64) μg/L(P< 0.05)in diabetic patients. No difference was found between obese and non-obese subjects. Positive correlation existed between visfatin and HbA1c(r=0. 317,P<0.01). Multiple linear step-wise regression showed that HbA1c and fasting plasma glucose had independent relation with the visfatin level. The result suggests that plasma visfatin may be related to glueometabolism and may play a role in the development of type 2 diabetes.