Effects of gonadotropin-releasing hormone analogue on linear growth and final height in girls with central precocious puberty

VernacularTitle:GnRHa治疗对中枢性性早熟女孩线性生长和成年身高的影响
Author: Shaoke CHEN ; Qin TANG ; Xin FAN ; Xianming GUO
Publication Type:Journal Article
Keywords: Gonadotropin-releasing hormone analogues; Precocious puberty; Girls; Final height
From: Chinese Journal of Endocrinology and Metabolism 2009;25(3):303-305
CountryChina
Language:Chinese
Abstract: The effect of gonadotropin-releasing hormone analogue(GnRHa) on lineafity growth and final height in 82 girls with central precocious puberty (CPP) was evaluated. The growth velocity in the second year was positively correlated with the difference value of bone age between the first year and the second year after treatment. The height standard deviation score for bone age and predicted aduh height increased after treatment. Twenty-six girls who had been followed to final height obtained better adult height than target height. GnRHa in combination with aerobic exercise increases linear growth and final height in girls with CPP.