Correlation of serum cystatin C with left ventricular hypertrophy in maintenance hemodialysis patients

VernacularTitle:维持性血液透析患者血清胱抑素C浓度与左心室肥厚的相关分析
Author: Xiaoyun SI ; Xiaohong BI ; Ying YAO ; Ping LE ; Xiaoyan WU
Publication Type:Journal Article
Keywords: Hemodialysis; Cystatin C; Hypertrophy,left ventricular
From: Chinese Journal of General Practitioners 2009;8(7):480-482
CountryChina
Language:Chinese
Abstract: The clinical data and routine biochemical parameters of 64 maintenance hemodialysis (MHD)patients and 20 controls were analyzed in the study.Serum cystatin C levels were detected by latex particle enhalice inununo-turbidimetry:and the cardial structure and function were assessed by echocardiography.As MHD time extended,the levels of semm cystatin C increased gradually,accompanied with high incidence of left ventricular hypertrophy(LVH).The LVH-positive patients had higher systolic blood pressure and left veHtricular mass index,and had higher serum cystatin C than tllose in LVH-negative patients.The serum cystatin C levels were positively correlated with left yentricular mass index(r=0.633,P<0.01)and systolic blood pressure(r:0.397,P<0.01).The results suggest that serum cystatin levels may be an influencing factor for long-term cardiacvascular complication in MHD patients.