Comparison of the effects of penequinine hydrochloride and atropine on the cardiovascular stability about preoperative in children
10.3760/cma.j.issn.1008-6706.2009.06.032
- VernacularTitle:戊乙奎醚与阿托品对幼儿术前用药时心血管稳定性的比较
- Author:
Peng ZHANG
;
Gang LIU
;
Xiaohui PENG
;
Qijun XIONG
;
Xiaofan ZHANG
- Publication Type:Journal Article
- Keywords:
Peneclidine hydrochloride;
Atropine;
Premedication;
Cardiovascular stability
- From:
Chinese Journal of Primary Medicine and Pharmacy
2009;16(6):1017-1018
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of penequinine hydrochloride and atropine on the cardiovascu-lar stability about preoperative in children by monitoring and recording the HR, MAP, SpO2, ECG changes. Methods 40 children underwent selective operation were randomly divided into two groups, 20 in each group. Penequinine hydrechloride group(group A) and atropine group(group B) were injected intramuscularly with penequinine hydro-chloride 0. 015mg/kg or atropine 0. 015mg/kg respectively, at 30 minutes before operation. Patients' HR, MAP, SpO2 and ECG changes were recorded at 10min,20min,30min and 40min after injection. Results The HR,MAP,SpO2 levels of group A and SpO2 level of group B had no significant changes. There are significant changes in HR,MAP of group B. Conclusion Penequinine hydrochloride can be used as preoperative medication and it is conducive to the maintenance of cardiovascular stability.
