Diagnostic significance of procalcitonin for postoperative infections in patients with bone fractures
10.3760/cma.j.issn.1674-2397.2009.03.008
- VernacularTitle:血清降钙素原在骨折患者术后感染中的诊断价值
- Author:
Weifang SUN
;
Bo LIU
- Publication Type:Journal Article
- Keywords:
Caleitonin;
Fractures,bone;
Infections
- From:
Chinese Journal of Clinical Infectious Diseases
2009;2(3):159-161
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of procalcitonin(PCT),C-reactive protein (CRP)and WBC counts in predicting the postoperative jnfections in patients with bone fractures.Methods Clinical data of 49 patients with open fractures were retrospectively analyzed,and the patients were grouped into the infeeted(n=24)and non.infected(n=25).PCT,CRP and WBC values were detected 1,4,7and 10 days after the operations,and the results were compared with those taken from the healthy controls.Areas under the receiver operating characteristic(ROC)curves were used to determine the value in predicting postoperative infections.Results PCT,CRP and WBC values in the infected group and the noninfected group were higher than those in health controls(F=19.84,57.71 and 35.44,P＜0.01).PCT,CRP and WBC values in the infected group were higher than those in the non-infected group 4.7 and 10 days after the operations(tPCT=7.31,7.74 and 4.59;tCRP=2.23,5.75 and 8.01;tWBC=2.34,2.51 and 4.07,P＜0.05).ROC curves suggested that PCT value was more sensitive and had higher specificity than CRP and WBC values in the diagnosis of postoperative infections.Conclusions PCT,CRP and WBC values arise in bone fracture patients with postoperative infections.Detection of PCT has higher sensitivity and specificity.which can be used in early diagnosis of postoperative infections.
