Relationship between adipocyte fatty acid-binding protein and metabolic syndrome
10.3760/cma.j.issn.1000-6699.2009.03.017
- VernacularTitle:脂肪细胞型脂肪酸结合蛋白与代谢综合征相关
- Author:
Qiugui LI
;
Jianhua JIANG
;
Bao ZHANG
;
Tai MA
;
Yongkang XIAO
- Publication Type:Journal Article
- Keywords:
Adipocyte fatty acid-binding protein;
Obesity;
Metabolic syndrome
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(3):299-300
- CountryChina
- Language:Chinese
-
Abstract:
Serum adipocyte fatty acid-binding protein (A-FABP) was raised in metabolic syndrome (MS)patients (n= 121) as compared with age-matched healthy subjects [n = 120, (14.7±4.8 vs 6.8 ±3. 0) μg/L,P<0.001]. It reached higher level in MS subjects with visceral obesity [(15.7±4.2 vs 12.6±5.1) μg/L, P<0.001]. Serum A-FABP concentration was positively correlated with body mass index, waist circumference, waist-tohip ratio, fasting insulin, homeostasis assessment for insulin resistance (HOMA-IR), fasting glucose, triglycerides,total cholesterol,and mean arterial blood pressure, whereas negatively correlated with HDL-C (r =-0. 448, P< 0.001).