Advances in the research of gene therapy for chondral lesions
10.3760/cma.j.issn.1673-4181.2009.03.011
- VernacularTitle:软骨损伤的基因治疗研究进展
- Author:
Lixue ZOU
;
Qixin ZHENG
- Publication Type:Journal Article
- Keywords:
Gene therapy;
Cartilage repair;
Cytokine
- From:
International Journal of Biomedical Engineering
2009;32(3):172-176
- CountryChina
- Language:Chinese
-
Abstract:
Cartilage injury has a very limited capacity of recovery by itself due to the lack of blood vessel in cartilage tissues. Current studies indicate that many kinds of cytokines have the function of promoting cartilage formation or repairing the injured cartilage with cartilage-like tissues. Cell-mediated transfer of the respective genes may ideally combine the supply of a chondrogenic cell population with the production of certain factors se-creted from the lesion and to promote the repairing of the lesion, which is considered the best treatment. Gene therapy based on this technology has developed rapidly in recent years. This review aims to summarize some of the development of the research in the field.
