Isolation,characterization and application of umbilical cord mesenchymal stem cells in the treatment of liver diseases
10.3760/cma.j.issn.1673-4181.2009.03.015
- VernacularTitle:脐带间充质干细胞的分离鉴定及肝病治疗的研究进展
- Author:
Jiao LI
;
Zhengyan ZHU
- Publication Type:Journal Article
- Keywords:
Umbilical core;
Mesenchymal stem cells;
Liver diseases;
Cell therapy
- From:
International Journal of Biomedical Engineering
2009;32(3):190-193
- CountryChina
- Language:Chinese
-
Abstract:
Human umbilical cord (UC) has been attracting increasing research effort in recent years.Since UC is a postnatal organ discarded after birth,the collection of its cells is non-invasive and raises no ethical con-cerns.Human umbilical cord provides large amount of mesenchymal stem cells(MSCs) which hold unlimited ca-pability of proliferation and great potential of differentiation and. MSCs have stable biological properties and low-er immunogenicity and can function well after amplifications.Studies have demonstrated that MSCs have the po-tential of inhibiting inflammatory response, generation of fibrosis, apoptosis and stimulating regeneration of hepa-tocytes.Therefore, UCMSCs could be an ideal cell source for the therapy of liver diseases.
