Compliance With sepsis bundles and its impact on mortality rate in patients with septic shock

VernacularTitle:集束治疗感染性休克的依从性及其对患者病死率的影响
Author: Ruiqiang ZHENG ; Qihong CHEN ; Hua LIN ; Nianfang LU ; Jiangquan YU ; Jun SHAO
Publication Type:Journal Article
Keywords: Sepsis shock; Bundles therapy; Compliance; Mortality rate
From: Chinese Journal of Clinical Infectious Diseases 2009;2(3):162-164
CountryChina
Language:Chinese
Abstract: Objective To evaluate the compliance of sepsis bundles and its impact on the mortality rate in patients with sepsis shock.Methods Fifty-eight adult patients with sepsis shock admitted in the intensive care units from January to December 2007 were enrolled in the study,and the compliance with the 6-h bundle was analyzed.Age,gender,sites of infection,acute physiology and chronic health evaluation II (APACHE II)score,duration of mechanical ventilation,ICU stay and the mortality rate were compared between patients completed 6-h bundles and those not completed 6-h bundles.Results Compliance with the 6-h bundle was obtained in 22 out of 58 patients(37.9%).Patients receiving bundle care had shorter duration of mechanical ventilation and shorter length of ICU stay than non-bundle patients(t=-2.225 and -3.702,P=0.037 and 0.001,respectively),and the mortality rate in 6-h bundle patients was also lower (X2=10.236,P=0.000).Conclusion The application of 6-h bundle care can reduce the mortality rate of the patients with sepsis shock.and the compliance should be improved.