Study of supervised aerobic exercise on physical activity, quality of life and psychological status in patients with systemic lupus erythematosus
10.3760/cma.j.issn.1007-7480.2009.07.004
- VernacularTitle:有氧运动对系统性红斑狼疮患者运动能力生活质量和心境影响的临床研究
- Author:
Minhua LU
;
Shunle CHEN
;
Shuang YE
;
Huiru WANG
;
Li KONG
;
Qian CHEN
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Aerobic exercise;
Exercise ability;
Quality of life;
Psychological and mood states
- From:
Chinese Journal of Rheumatology
2009;13(7):443-446
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of medical supervised aerobic exercise on physical activity, quality of life and psychological status in patients with systemic lupus erythematosus (SLE). Methods SLE patients who fulfilled ACR criteria were recruited and divided into 2 groups: exercise group (n=24) and control group (n=25). The patients in the exercise group were supervised to have aerobic exercises. The intensiveness of exercise was determined by 20%-40% of maximum heart rate reservation. Visual analog scale (VAS), SLE disease activity index (SLEDAI) score, physical working capacity (PWC170), SF-36 and profile of mood states (POMS) of the two groups were used to evaluate the changes at the baseline, 1 month, 3 months and 6 months after this study. Results The 2 groups were homogeneous and comparable in disease activity at baseline. 1, 3 and 6 months after the study, the VAS, PWC170, POMS and SF -36 of SLE patients were improved in certain degrees in both groups, while the improvement of VAS (P<0.05), PWCITO (P< 0.01 ) and social function of SF-36 (P<0.05) of exercise group were significantly more evident than those of the control group in 6 months after study without any impact on disease condition. There was a high negative correlation between VAS and 5 categories of POMS (r=-6.26~-0.393, P<0.01 ) and a more relevant positive association between VAS and 2 categories of POMS (r=0.534~0.611, P<0.01). Conclusion The data demonstrate that the supervised aerobic exercise can ameliorate physical capacity, improve quality of life and psychological and emotional status in the state SLE patients without aggravating disease per se.
