Serum Lipoprotein(a) in Diabetic Retinopathy Patients.
- Author:
Ho Chun LEE
1
;
Ha Kyoung KIM
;
Hyung Chan KIM
Author Information
1. Department of Ophthalmology, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Diabetic retinopathy;
Lipoprotein(a);
Risk factor
- MeSH:
Apolipoprotein B-100;
Apoprotein(a);
Blood Pressure;
Cardiovascular Diseases;
Cholesterol;
Diabetic Retinopathy*;
Diagnosis;
Humans;
Lipoprotein(a)*;
Risk Factors;
Triglycerides
- From:Journal of the Korean Ophthalmological Society
1995;36(6):930-937
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lipoprotein(a), a complex formed by apolipoprotein(a), apo B-100 and lipids, is considered an independent, genetically determined, predictor of cardiovascular disease. It may have antifibrinolytic properties in view of its similarity to plasmmogen. To evaluate whether lipoprotein(a) may be a risk factors in patients with diabetic retinopathy or not, we measured the circulating serum level of lipoprotein(a) in each group classified by the severity of diabetic retinopathy and control group. The serum lipoprotein(a) level was higher in the diabetic patients than in the control group, and diabetic retinopathy, which was expressed by the grade of retinopathy in the worse eye, was correlated significantly with the duration of disease, and the serum level of lipoprotein(a) independently(P<0.05). There was no correlation between the diabetic retinopathy and the age at the time of diagnosis, systolic or diastolic blood pressure, or the serum levels of HbA(IC), cholesterol, triglyceride, and total lipid. We concluded that the lipoprotein(a) may play a role as one of the independent risk factors in diabetic retinopathy.
