Five cases of childhood primary Sjogren's syndrome and literature review

VernacularTitle:儿童原发性干燥综合征五例并文献复习
Author: Yubo CAI ; Weiqi ZHANG ; Lanfang CAO ; Yueying GU
Publication Type:Journal Article
Keywords: Child; Sjogren's syndrome; Farotitis
From: Chinese Journal of Rheumatology 2009;13(7):473-476
CountryChina
Language:Chinese
Abstract: ObjectiveTo further understand the clinic manifestations of childhood primary Sjogren's Syndrome(pSS) and enhance early diagnosis. MethodsFive cases of pSS from Renji Hospital, Shanghai, were reported and their clinical features were analysoed. And literatures from Medline database and Weipu database were reviewed and discussed. Results①Childhood pSS had various clinic presentations that were non-specific and sicca symptoms were absent or occur late in most cases. ② The most common presentations were recurrent parotiditis and cutaneous manifestations with various locations and forms. ③ American-European Criteria for SS were not suitable for the diagnosis of childhood pSS. ConclusionRecurrent parotiditis and cutaneous manifestations in children can be used as clues for the diagnosis of childhood pSS but needs to be further confirmed by the positive results of salivary gland biopsy and autoantibodies examination, particularly SSA/SSB.