Observation of curative effect of repeated botulinium toxin type A treatment for Meige's syndrome in senile people
10.3760/cma.j.issn.0254-9026.2009.07.018
- VernacularTitle:老年人Meige综合征的A型肉毒毒素重复治疗观察
- Author:
Yuanfei DENG
;
Wenshuang ZENG
;
Xiaohua WANG
- Publication Type:Journal Article
- Keywords:
Meige Syndrome;
Botulinum toxin type A;
Treatment outcome
- From:
Chinese Journal of Geriatrics
2009;28(7):584-586
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of repeated botulinum toxin type A (BTX-A) treatment for Meige's syndrome in senile people. Methods Forty-eight senile patients with Meige's syndrome received BTX-A treatment for twelve times or over. The improvements of spasm were evaluated before and after the first, the sixth and the twelfth treatment according to Cohen's criteria. The onset time, effective duration and side effects were studied and compared among the three times treatments. Results The obvious effective rate of the three times treatment were all 100%. The average onset time of the three times treatments were (3.5± 1.7)days,(3.2±1.8)days and (3.3±1.9)days, and the average effective duration were (25.4±2.1)weeks,(24.6±2.3)weeks and (25.4±1.8)weeks, respectively. The incidences of side effects were 8. 3% (4/48), 6.3(3/48)%and 8.3%(4/48), respectively. All the differences were not statistically significant(P>0.05). Conclusions Repeated BTX-A treatment is an effective and safe method for Meige's syndrome in senile people.
