The curative effect of recombinant human interferon α-2b gel on flooding prevention in loop electrosurgical excision procedure

VernacularTitle:重组人干扰素α-2b凝胶预防宫颈电热圈环形切除术中、术后出血的疗效观察
Author: Qi ZHOU ; Chun ZHANG
Publication Type:Journal Article
Keywords: Interferon alfa-2b; Uterine cervical diseases; Gynecologic surgical procedures; Postoperative hemorrhage
From: Chinese Journal of Postgraduates of Medicine 2009;32(21):19-22
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy of recombinant human interferon α-2b gel onflooding prevention in loop electrosurgical excision procedure (LEEP) during and after the operation.Method The 152 patients with cervical disease were randomly divided into three groups: group A(recombinant human interferon α-2b gel treatment group), group B (hypophysin treatment group)and groupC(control group). Results The amount of intraoperative bleeding and the amount of post-operative bleedingof the group A was (2.57±1.19) ml and (2.24±1.75) ml, the group B was (3.00±1.49) ml and (45.86±26.14) hal, the group C was (45.62±39.57) ml and (56.90±41.90) ml, respectively. There was no differencebetween group A and group B in the amount of intraoperative bleeding (P>0.05), but significantly less thangroup C (P<0.01). There was no difference between group B and group C in the amount of post-operativebleeding (P>0.05), but significantly much more than group A (P<0.01). Conclusion Recombinanthuman interferon α-2b gel is effective on reducing intraoperative and post-operative bleeding in LEEP.