The ras-mitogen activeted protein kinase pathway and target for cancer therapy
10.3760/cma.j.issn.1673-422X.2009.07.001
- VernacularTitle:ras-丝裂原浯化蛋白质激酶通路与肿瘤靶向治疗
- Author:
Hong YU
;
Xiumei MA
- Publication Type:Journal Article
- Keywords:
Signal transduction;
Mitogen-activated protein kinases;
Target for therapy
- From:
Journal of International Oncology
2009;36(7):483-485
- CountryChina
- Language:Chinese
-
Abstract:
The ras-mitogen activeted protein kinase pathway is responsible for regulation of many cel-lular processes, including differentiation, cytoskeletal organization, and protein trafficking. Much attention has been paid to them and their role in cancer therapy recently, and its inhibitor pathways are applied to clinical tes-ting, such as, Raf kinse inhibitors, MEK inhibitor, Src kinase inhibitor.
