Endobronchial metastasis from prostate cancer: analysis of cases and review of the literatures
10.3760/cma.j.issn.0254-9026.2009.07.010
- VernacularTitle:前列腺癌支气管黏膜转移一例并文献复习
- Author:
Zhigang ZHANG
;
Xinmin LIU
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasns;
Bronchial neoplasms;
Neoplasm metastasis;
Prostatespecific antigen;
Acid phosphatase
- From:
Chinese Journal of Geriatrics
2009;28(7):555-558
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical,radiologic and pathological features of endobronchial metastasis from prostate cancer, and its diagnosis and treatment. Methods Ten cases of endobronchial metastasis from prostate cancer with pathological evidence in our hospital were retrospectively analyzed.The clinical, radiologie andpathological features and the diagnostic procedures and treatment of the cases were reported and analyzed while combined with literature. ResultsAn average age at diagnosis of advanced prostate cancer was 65.5 years. Emoptysis(5/10), cough (4/10), dyspnea (4/10) and weight loss (5/10) were the common symptoms.Chest X-ray disclosed hilar and mediastinal lymphadenopathy (4/10), hilar mass (3/10) or atelectasis (2/10) . Bronchoscopic examination revealed that most of lesion located in single lobar or segmental bronchus (6/10). Bilateral upper lobe were most susceptibly involved(7/10). Polypoid lesions or mass in lumen of bronchi(8/10)were more frequent than infiltrative lesion(2/10), which could obstruct the orifice of the bronchi in different extent. Immunohistochemical staining for prostate specific antigen or prostatic acid phosphatase was positive, and most patients responded well to endocrine therapy. Conclusions Clin.ical and radiologic features of endobronchial metastasis from prostate cancer are similar to those of primary bronchogenic carcinoma. Immunohistoehemical study is helpful for differential diagnosis and the short-term efficacy of endocrine therapy is significant.
