Recent progress on the research of microRNA in cance
10.3760/cma.j.issn.1673-422X.2009.07.003
- VernacularTitle:微小RNA在肿瘤研究方面的进展
- Author:
Lei CHEN
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplasms;
Oncogenes;
Genes,tumor suppressor
- From:
Journal of International Oncology
2009;36(7):489-491
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA (miRNA) regulate the expression of target mRNA according to the specific base pairing. They are involved in proliferation,differentiation and apoptosis of cells. The expression of miRNA has distinct differences between normal tissues and cancers, miRNA can be oncogenes but also suppressor genes, they play an important role in cancer. And miRNA are promising to be a new therapeutic target. In this review, we will discuss the advance in the research of miRNA in cancer.
