Expression and significance of B7-H4 in the tumor
10.3760/cma.j.issn.1673-422X.2009.07.006
- VernacularTitle:肿瘤组织中B7-H4的表达及意义
- Author:
Liting GUO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
B7- H4
- From:
Journal of International Oncology
2009;36(7):497-499
- CountryChina
- Language:Chinese
-
Abstract:
B7-H4 is a new member of costimulatory molecules,it negatively regulates T cell immunity by the inhibition of T cell proliferation, cytokine production, and cell cycle progression. Recent studies indicate that B7- H4 is associated with the generation and progression of tumor and is an important indication in the diag-nosis and treatment of tumor.