Reserch development on the correlation of Bcl-2 family and tumor radiosensitivity
10.3760/cma.j.issn.1673-422X.2009.07.009
- VernacularTitle:Bcl-2家族与肿瘤放射敏感性关系的研究进展
- Author:
Mi CHEN
;
Xiangying XU
- Publication Type:Journal Article
- Keywords:
Genes,Bcl-2;
Neoplasms;
Radiosensitivity;
Apoptosis
- From:
Journal of International Oncology
2009;36(7):504-506
- CountryChina
- Language:Chinese
-
Abstract:
Bcl-2 family plays an important role in cell apoptosis pathway. The ratio of pro-apoptosis members and anti-apoptosis members closely correlates with tumorigenesis, tumor radiosensitivity and progno-sis. Recent years ,according to the correlation of Bcl-2 family and tumor radiosensitivity, many researchers want to find new therapeutic strategies that target Bcl-2 in clinical radiotherapy.