Target therapy in metastatic renal cell carcinoma
10.3760/cma.J.jssn.1673-422X.2009.07.018
- VernacularTitle:转移性肾细胞癌的靶向治疗研究进展
- Author:
Xianjin DU
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Targeted agents
- From:
Journal of International Oncology
2009;36(7):530-533
- CountryChina
- Language:Chinese
-
Abstract:
The targeted agents of metastatic renal cell carcinoma include the inhibitor of the VHL- HIF-VEGF pathway(sunitinib、 sorafenib、 bevacizumab、 Axitinib) and the mTOR pathway (Temsirolimus, Everoli-mus). These targeted chugs suggest the onset of a new therapeutic era for patients with metastatic renal cell car-cinoma. It is necessary to pay more attention to the side effect. The therapeutic scheme choice of patients and the treatment effect of the non-clear cell carcinomal need further studies.
