Hilar Cholangiorarcinoma of 204 cases

Yue Wang; Chunlin GE; Jun Zhang; Jinnian GE; Jun Gao; Ji Luo

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Hilar Cholangiorarcinoma of 204 cases

VernacularTitle:204例肝门部胆管癌的临床分析
Author: Yue WANG ; Chunlin GE ; Jun ZHANG ; Jinnian GE ; Jun GAO ; Ji LUO
Publication Type:Journal Article
Keywords: Bile duct neoplasms; Prognosis; Biliary tract surgical procedures
From: Chinese Journal of General Surgery 2009;24(7):529-531
CountryChina
Language:Chinese
Abstract: Objective To investigate the surgical effect of hilar cholangiocarcinoma and its impact on prognosis. Method The clinical data of 204 hilar cholangiocarcinoma admitted into the First Hospital of China Medical University were retrospectively analyzed. According to the Bismuth-corlette type, type Ⅰ was 18 cases, type Ⅱ 40 cases, type Ⅲ-a 30 cases, type Ⅲ-b 53 cases, type Ⅳ 57 cases. The other 6 cases was not typed. Color Doppler ultrasound, CT, MRCP were used to determine the Bismuth-Corlette type before the surgery. Based on preoperative image diagnosis the correct diagnosis rate was 53. 7%, 76. 4%, 100% for ultrasound, CT and MRCP respectively. Ninety-two cases underwent tumor resection, including radical resection (R0) in 55 cases, and palliative resection (R1, R2) in 37 cases. Ninety-eight cases underwent exploration and biliary drainage, 6 cases did laparotomy only, 2 cases received liver transplantation. The survival rate (P < 0. 001) is statistically different between patients receiving tumor resection and those not. Radical resection and palliative resection group are also statistically different in survival rates (P < 0. 05). Cox multivariate analysis shows that operation pattern, histological differentiation are two independent prognostic factors. Conclusion Surgery is the main method to treat hilar cholangiocarcinoma and radical resection could achieve the best effect. Reasonable perioperative treatment could reduce the complications and mortality.