Genetic modification of bone marrow stem cells in treatment of hind limb ischemia
10.3760/cma.j.issn.1673-4203.2009.08.015
- VernacularTitle:基因修饰骨髓干细胞治疗下肢缺血的研究进展
- Author:
Yulong WANG
;
Jinchi ZHANG
- Publication Type:Journal Article
- Keywords:
gene therapy;
stem cells;
hindlimb ischemia10. 3760/cma. j. issn. 1673-4203. 2009.08.015
- From:
International Journal of Surgery
2009;36(8):538-541
- CountryChina
- Language:Chinese
-
Abstract:
With the development of gene technology,it is gradually possible and much better for genetic modification of bone marrow stem cells in treatment of hindlimb ischemia. Gene modification of cells prior to their transplantation, especially stem cells, enhances their survival and increases their function in cell therapy. But this treatment is only used for the experimental stage. Here, we review the current uses of gene-modified bone marrow stem cells in vascular disease.