Effect of Ruigan on liver function of Perioperative Treatment in Obstructive Jaundice

VernacularTitle:门冬氨酸鸟氨酸对阻塞性黄疸患者围手术期肝功能的影响
Author: Bozhi CHEN ; Kanglin ZHONG
Publication Type:Journal Article
Keywords: obstructive jaundice; Ruigan(L-omithine-L-aspartate); liver function; endotoxin
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(7):1248-1249
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of Ruigan (L-omithine-L-aspartate) on liver function of perio-perative treatment. Methods 58 patients with obstructive jaundice and having been done operation were randomly di-vided into two groups:ruigan group (cured group,32 cases) and routine hugan group (control group,26 cases). The levels of liver function and endotoxin were detected when being in hospital, before operation and after operation re-spectively. Results Treatment with ruigan could improve the liver function in perioperation, which has significant difference when compared to the control group (P < 0.05).. Ruigan could reduce the level of endotoxin before and af-ter operation (P < 0.05) and improve endotoxaemia in obstructive jaundice. Conclusion Ruigan would improve the liver function and the endotoxaemia in the perioperative obstructive jaundice.