Therapeutic Effect of Shuguanling Mixture on High-sensitivity C-reactive Protein and Blood Lipids in Patients of Unstable Angina Pectoris
10.3760/cma.j.issn.1673-4246.2009.04.003
- VernacularTitle:舒冠灵合剂对不稳定性心绞痛高敏C反应蛋白和血脂的影响
- Author:
Jing LIU
- Publication Type:Journal Article
- Keywords:
Unstable angina pector;
High-sensitivity C-reactive protein;
Shuguanling mixture
- From:
International Journal of Traditional Chinese Medicine
2009;31(4):296-298
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effect of Shuguanling mixture on high-sensitivity C-reactive protein (hs-CRP) and blood lipids of patients with unstable angina pectoris (UAP). Methods 110 patients with UAP were randomly recruited into a control group and a treatment group, with 50 patients in the control group and 60 in the treatment group. The control group was treated with conventional treatment (aspirin, β-receptor block agent, and nitrate), while the treatment group was treated with Shuguanling mixture on the basis of conventional treatment. Both groups received thetreatment for 30 days. Results The total effective rate of pectoris treatment was 78.3% and 66% respectively in the treatment group and the control group, and the effective rate showed in ECG was 63.3% and 46% respectively in both groups. The treatment group demonstrated a significant superiority to the control group. The values of TC, TG, LDL-C and hs-CRP in both groups were decreased but HDL-C increased in the treatment group after the treatment. Except for TC, the difference of values was significance between the two groups. Conclusion In the treatment of UAP,Shuguanling mixture is effective in ameliorating symptoms and ECG results, lowering hs-CRP and blood lipids and so thus reducing the rate of adverse reaction dramatically.