Value of IHb map in the diagnosis of coiorectal lesions

VernacularTitle:内镜下血红蛋白指数色图测定诊断大肠病变的价值
Author: Jiaolian CHEN ; Chuqing HUANG ; Weirun ZHONG ; Pinghu CHEN
Publication Type:Journal Article
Keywords: Index of hemoglobin; Colorectal lesions; Colonoscopy; Microvessel density
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(7):1215-1216
CountryChina
Language:Chinese
Abstract: Objective To evaluate the value of IHb map in colorectal lesions. Methods IHb map images was observed in 267 patients with colorectal lesions using colonoscopy. Biopsies were taken and microvessel density (MVD) were examined by immunohistochemical staining. Results Colorectal polyps were found in 133 patient,IHb values were higher in inflammatory and adenomatous polyps,and IHb values of hyperplastic polyps were significantly lower than that of inflammatory polyps(P < 0.01). IHb values were higher in the specimens of more inflammatory cell infiltration than normal mucosa (P < 0.05). IHb values seemed to be related to tumor differentiation. An increased IHb values was more frequently observed in differentiated carcinoma than in undifferentiated carcinoma(P < 0.05). The higher of IHb values, the higher of MVD (P < 0.01). Conclusion To oporate IHb map is simple, measurement of IHb map is useful in detecting minimal lesion in colorectal lesions,distingnishing the benign from the malignant,de-termining the extent of the lesion and do endoscopic treatment timely.